Search on: SMAD7 PROTEIN 
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Descriptor English:   Smad7 Protein 
Descriptor Spanish:   Proteína smad7 
Descriptor Portuguese:   Proteína Smad7 
Synonyms English:   Madh7 Protein  
Tree Number:   D12.644.360.024.334.200.700
D12.776.157.057.170.249.700
D12.776.476.024.428.249.700
Definition English:   An inhibitory smad protein that associates with TRANSFORMING GROWTH FACTOR BETA RECEPTORS and BONE MORPHOGENETIC PROTEIN RECEPTORS. It negatively regulates SIGNAL TRANSDUCTION PATHWAYS by inhibiting PHOSPHORYLATION of RECEPTOR-REGULATED SMAD PROTEINS. 
History Note English:   2006(1997) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   50787 
Unique Identifier:   D051906 

Occurrence in VHL:
 

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